Open AccessBasket catheter-guided ultra-high-density mapping of cardiac arrhythmias: a systematic review and meta-analysis
Author(s) -
Fares-Alexander Alken,
Shaojie Chen,
Mustafa Masjedi,
Helmut Pürerfellner,
Philippe Maury,
Claire Martin,
Frédéric Sacher,
Pierre Jaı̈s,
Christian Meyer
Publication year - 2020
Publication title -
future cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.392
H-Index - 33
eISSN - 1744-8298
pISSN - 1479-6678
DOI - 10.2217/fca-2020-0032
Subject(s) - medicine , catheter ablation , ablation , atrial fibrillation , atrial tachycardia , meta analysis , cardiology , tachycardia , ventricular tachycardia , randomized controlled trial , prospective cohort study
Aim: Ultra-high-density mapping (HDM) is increasingly used for guidance of catheter ablation in cardiac arrhythmias. While initial results are promising, a systematic evaluation of long-term outcome has not been performed so far. Methods: A systematic review and meta-analysis was conducted on studies investigating long-term outcome after Rhythmia HDM-guided atrial fibrillation (AF) or atrial tachycardia catheter ablation. Results: Beyond multiple studies providing novel insights into arrhythmia mechanisms, follow-up data from 17 studies analyzing Rhythmia HDM-guided ablation (1768 patients, 49% with previous ablation) were investigated. Cumulative acute success was 100/90.2%, while 12 months long-term pooled success displayed at 71.6/71.2% (AF/atrial tachycardia). Prospective data are limited, showing similar outcome between HDM-guided and conventional AF ablation. Conclusion: Acute results of HDM-guided catheter ablation are promising, while long-term success is challenged by complex arrhythmogenic substrates. Prospective randomized trials investigating different HDM-guided ablation strategies are warranted and underway.