Open AccessEvaluating patients' satisfaction and preferences with a secondary prevention cardiovascular polypill: the Aurora Study
Author(s) -
Juan Cosı́n-Sales,
José Murcia-Zaragoza,
Hector O Pereyra-Rico,
Fernando de la Guía-Galipienso,
Kurt Hermans,
Gabriel Sampol Rubio
Publication year - 2021
Publication title -
journal of comparative effectiveness research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.567
H-Index - 23
eISSN - 2042-6313
pISSN - 2042-6305
DOI - 10.2217/cer-2021-0105
Subject(s) - polypill , medicine , observational study , patient satisfaction , family medicine , medication adherence , post hoc analysis , post hoc , cross sectional study , secondary prevention , physical therapy , surgery , disease , pathology
Aim: To evaluate the satisfaction, preferences and adherence of patients in secondary cardiovascular prevention treated with the Spanish National Cardiovascular Research Centre cardiovascular polypill compared with patients treated with the separate monocomponents. Methods: Observational, cross-sectional and multicenter study. Satisfaction was evaluated by the Treatment Satisfaction Questionnaire for Medication 9 items, adherence by the Morisky-Green questionnaire and ad-hoc questions were asked regarding patient preferences. Results: Polypill patients reported higher satisfaction than patients treated with the monocomponents (77.3 vs 71.2%; p < 0.0001). 72.8% of patients treated with the monocomponents would prefer to change to the polypill. Patients treated with the polypill had significantly higher adherence than patients treated with the monocomponents (57.7 vs 41.1%; p = 0.0027). Conclusion: Polypill patients show higher satisfaction and better adherence. Most patients receiving the monocomponents would prefer a polypill regime.