Open AccessNational Early Warning Score 2 and laboratory predictors correlate with clinical deterioration in hospitalized patients with COVID-19
Author(s) -
Gülşah Tunçer,
Serkan Sürme,
Osman Faruk Bayramlar,
Hatice Kübra Karanalbant,
Betül Çopur,
Meltem Yazla,
Esra Zerdalı,
İnci Yılmaz Nakir,
Ayse Rk Cinar,
Ahmet Buyukyazgan,
Hatice Balli,
Yeşim Kürekçi,
Serap Şimşek-Yavuz,
Mehmet Mesut Sönmez,
Gönül Şengöz
Publication year - 2021
Publication title -
biomarkers in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 44
eISSN - 1752-0371
pISSN - 1752-0363
DOI - 10.2217/bmm-2021-0061
Subject(s) - medicine , procalcitonin , early warning score , covid-19 , odds ratio , logistic regression , emergency medicine , sepsis , disease , infectious disease (medical specialty)
Aim: We aimed to determine the prognostic values of the National Early Warning Score 2 (NEWS2) and laboratory parameters during the first week of COVID-19. Materials & methods: All adult patients who were hospitalized for confirmed COVID-19 between 11 March and 11 May 2020 were retrospectively included. Results: Overall, 611 patients were included. Our results showed that NEWS2, procalcitonin, neutrophil/lymphocyte ratio and albumin at D0, D3, D5 and D7 were the best predictors for clinical deterioration defined as a composite of ICU admission during hospitalization or in-hospital death. Procalcitonin had the highest odds ratio for clinical deterioration on all days. Conclusion: This study provides a list of several laboratory parameters correlated with NEWS2 and potential predictors for clinical deterioration in patients with COVID-19.