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Current State of Hormone Replacement Therapy: The Case for Using Trimegestone
Author(s) -
May Wahab,
Farook AlAzzawi
Publication year - 2006
Publication title -
women s health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.363
H-Index - 39
eISSN - 1745-5065
pISSN - 1745-5057
DOI - 10.2217/17455057.2.4.539
Subject(s) - progestogen , estrogen , medicine , endometrial hyperplasia , uterus , hormone replacement therapy (female to male) , hormone therapy , estrogen replacement therapy , vasomotor , hormone , gynecology , physiology , hyperplasia , testosterone (patch) , breast cancer , cancer
Estrogen deficiency has a negative impact on the quality of life of postmenopausal women and is associated with vasomotor symptoms, insomnia and emotional lability. Other manifestations of estrogen deficiency include dry skin, dry vagina and dyspareunia, in addition to bone loss. Estrogen replacement effectively reverses these changes. The only indication for the administration of a progestogen is to protect the postmenopausal uterus against the potential development of endometrial hyperplasia and carcinoma.

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