Open AccessEFFICACY OF CATFISH (PANGASIUS HYPOPHTHALMUS) OIL TO OVERCOME STUNTING BY REDUCING INFLAMMATORY CONDITION
Author(s) -
Sepsina Reski,
Farmaditya Ep Mundhofir,
Etisa Adi Murbawani,
Yora Nindita,
Muflihatul Muniroh,
Fronthea Swastawati,
Endang Mahati
Publication year - 2021
Publication title -
international journal of pharmacy and pharmaceutical sciences/international journal of pharmacy and pharmaceutical sciences
Language(s) - English
Resource type - Journals
eISSN - 2656-0097
pISSN - 0975-1491
DOI - 10.22159/ijpps.2021v13i5.40357
Subject(s) - catfish , pangasius , body weight , zoology , food science , biology , veterinary medicine , medicine , fish <actinopterygii> , fishery
Objective: This study aimed to evaluate the effect of catfish (Pangasius hypophthalmus) oil on hs-CRP and transthyretin levels of undernourished Wistar rats.
Methods: Thirty male Wistar rats were divided into five equal groups. Healthy control (KN) is normal rats that consumed a standard diet only and negative control (K-) is undernourished rats that consumed a protein-free diet only. Undernourished rats that consumed a protein free diet and catfish (Pangasius hypophthalmus) oil at doses 0.020 ml/200 g-body-weight/d, 0.040 ml/200 g-body-weight/d and 0.060 ml/200 g-body-weight/d were classified to P1, P2 and P3 groups, respectively. Hs-CRP is a parameter to evaluate inflammatory condition. Transthyretin and body weight are parameters for measuring nutritional status.
Results: Treatment of catfish (Pangasius hypophthalmus) oil on P3 group significantly increases body weight of rats (p 0.05) compared to K-.
Conclusion: The present study showed that catfish (Pangasius hypophthalmus) oil has the potential effect to increase body weight and reduce inflammatory biomarker (hs-CRP) levels but has no effect to increase TTR levels in undernourished Wistar rats.