Open AccessA CASE STUDY ON FOURNIER’S GANGRENE IN AN EPILEPTIC PATIENT WITH THE EMERGENCE OF ANTIBIOTIC RESISTANCE IN BACTERIA
Author(s) -
Sowjanya Mendem,
Aqib Ali Faraz,
K. L. N. Rao
Publication year - 2020
Publication title -
international journal of pharmacy and pharmaceutical sciences/international journal of pharmacy and pharmaceutical sciences
Language(s) - English
Resource type - Journals
eISSN - 2656-0097
pISSN - 0975-1491
DOI - 10.22159/ijpps.2020v12i9.39003
Subject(s) - medicine , septic shock , antibiotics , gangrene , debridement (dental) , broad spectrum , blood supply , surgery , shock (circulatory) , antibiotic therapy , mortality rate , sex organ , antibiotic resistance , sepsis , biology , microbiology and biotechnology , chemistry , combinatorial chemistry , genetics
Fournier's gangrene is rare necrotizing soft tissue infection affecting the perianal, perineal, and genital areas. The mean age of the reported cases was found to be at 55 y, predominantly in men. It occurs due to insufficient blood supply to the affected areas, along with the presence of an infection. Delay in the treatment is associated with a higher mortality rate, up to 90%, as the condition might progress to septic shock and other complications. Treatment requires urgent surgical debridement of all the necrotic tissue along with high doses of broad-spectrum antibiotics. Empirical broad-spectrum antibiotic therapy is to be initiated as soon as possible until the results of the culture cause modifications in the therapy.