Open AccessEVALUATION OF DEPEGMENTING AND ANTIERYTHEMIC EFFECTS OF COSMETIC EMULGELS CONTAINING RASPBERRY FRUIT EXTRACT ON HUMAN CHEEK SKIN
Author(s) -
Rizwana Kausar,
Naveed Akhtar
Publication year - 2016
Publication title -
international journal of pharmacy and pharmaceutical sciences/international journal of pharmacy and pharmaceutical sciences
Language(s) - English
Resource type - Journals
eISSN - 2656-0097
pISSN - 0975-1491
DOI - 10.22159/ijpps.2017v9i1.15123
Subject(s) - erythema , chemistry , melanin , food science , medicine , dermatology , biochemistry
Objective: This research work was performed to discover the efficacy of newly formulated topical formulation (o/w) emulgel of Raspberry fruit extract against its base taken as a control on skin erythema and skin melanin. Methods: Concentrated Raspberry fruit extract was prepared by macerating fresh fruit in aqueous methanol under room temperature. This extract was then entrapped in the inner oily phase of o/w emulgel. Newly formulated, formerly evaluated base (without extract) and a formulation containing 4% concentrated extract of Raspberry were applied to cheeks of 13 healthy female human volunteers for a period of 12 w. Skin erythma and melanin were measured after every two weeks to evaluate any effect produced by this topical formulation. Results: Base showed insignificant (p≥0.05) while formulation showed a significant decrease in skin erythma. Skin melanin content was insignificantly decreased by base but significantly decreased by the formulation. The newly developed cosmetic emulgel of Raspberry fruit extract showed its effects without causing any irritation and was found to be suitable and safe dermatological formulation. Conclusion: Formulation was successfully evaluated for its dermatological effects. It was found to be a useful, harmless and cost effective skin whitening treatment derived from natural sources.