Open AccessREDUCED SUSCEPTIBILITY OF MRSA TO VANCOMYCIN
Author(s) -
Suneel Bhooshan,
Jyoti Prasad,
Amitesh Dutta,
KE Vandana,
Chiranjay Mukhopadhyay
Publication year - 2016
Publication title -
international journal of pharmacy and pharmaceutical sciences/international journal of pharmacy and pharmaceutical sciences
Language(s) - English
Resource type - Journals
eISSN - 2656-0097
pISSN - 0975-1491
DOI - 10.22159/ijpps.2016v8i9.13023
Subject(s) - vancomycin , microbiology and biotechnology , clindamycin , methicillin resistant staphylococcus aureus , linezolid , antibiotics , gentamicin , staphylococcus aureus , minimum inhibitory concentration , ciprofloxacin , agar dilution , medicine , biology , bacteria , genetics
Objective: This study was conducted to observe the antibiogram, vancomycin MIC (Minimum Inhibitory Concentration), and inducible clindamycin resistance in clinical isolates of MRSA (Methicillin-Resistance Staphylococcus aureus ). Methods: Drug resistance pattern was studied by Kirby-Bauer disc diffusion methods. MIC of vancomycin was determined by agar dilution method. Results: MRSA was found to be highly resistant to gentamicin (76%), erythromycin (67.03%) and ciprofloxacin (65.09%) while glycopeptides showed uniform susceptibility. Conclusion: Though there was no drug resistance observed against vancomycin and linezolid, it’s wise to use these antibiotics safely as emerging resistance has been reported for these drugs from all over the world.