Open AccessHISTOLOGICAL VARIANCES OF MORINGA OLIFERA ON THE KIDNEY OF ADULT WISTAR RATS
Author(s) -
Adetunji Opeyemi Adebola,
Oyewo O. Oluwatoyin,
Adetunji Iyabode Toyin,
Nwobi Nnena Linda
Publication year - 2021
Publication title -
innovare journal of medical sciences
Language(s) - English
Resource type - Journals
ISSN - 2321-4406
DOI - 10.22159/ijms.2021.v9i3.41144
Subject(s) - kidney , moringa , body weight , medicine , endocrinology , hepatocyte , traditional medicine , biology , in vitro , biochemistry
Aim and Objectives: Demonstrating the exact quantity of Moringa oleifera (MO) that will cure any hepatocyte diseases and the one that can harm the hepatocytes of the Adult Wistar rats.
Methods: Twenty (20) adult Wistar rats (both sex) were used for the study (caged based on same sex to avoid mating and pregnancy) and were randomly assigned into four groups (n=5); A-Control, B-250 mg/body weight (BW) of MO, C-500 mg/BW of MO, and D-750 mg/BW of MO orally.
Result: The crude aqueous extract of MO Lam, shows insignificant increased in BW at the 1st week of administration which latter dropped little by little doing the weeks of the administration in groups (B, C, and D) rats, by comparing (p<0.05) to the control group after MO administration, the organ (Kidneys) shows a significant difference between the kidneys (left and right kidneys) in relation to the control group rats. MO increases the weight of the animals morphologically by comparing the weight of the animals before and after administration. Histological sections shows a normal Glomerulli, Peri-Glomerular Space, Convoluted Tubules, and Interstitium, after administration of the Crude Aqueous Extract of MO lame in terms with the control group rats.
Conclusion: MO is a good herb that has no damage effect on the body and hepatocytes but of more beneficial.