Open AccessEVALUATION OF DRUG-DRUG INTERACTIONS IN PATIENTS OF GENERAL MEDICINE, ICU and EMERGENCY DEPARTMENTS AT A TERTIARY CARE HOSPITAL
Author(s) -
N. Vanitha Jyothi,
D R Bharathi,
G M Prakruthi
Publication year - 2018
Publication title -
international journal of current pharmaceutical research
Language(s) - English
Resource type - Journals
ISSN - 0975-7066
DOI - 10.22159/ijcpr.2018v10i3.27345
Subject(s) - polypharmacy , medicine , drug , observational study , emergency medicine , medical prescription , tertiary care , medical record , emergency department , prospective cohort study , drug interaction , medical history , medical emergency , intensive care medicine , pharmacology , psychiatry
Objective: To evaluate the drug-drug interactions in General medicine, ICU and Emergency departments.Methods: It is a prospective-observational study. This study included hospital In-patients treated in General medicine, ICU and Emergency. Data were collected from the medical records of In-patients which includes patient’s demographic details, medical history, social history, treatment chart, status and drug-drug interaction is assessed by using Lexicompand Medscape and other tertiary resources and documented in a suitably designed data collection form.Results: A total of 250 subjects were enrolled in the study. The majority (23.6%) of cases were identified in the age group 51–60 y old. Higher rate of DDIs was identified in the male gender prescriptions. 70% moderate interactions, 33.6% Minor interactions, 6.4% serious interaction found in General medicine, ICU and Emergency departments.Conclusion: Polypharmacy, age and comorbid condition were took part major role in drug-drug interactions.