EVALUATION OF DRUG-DRUG INTERACTIONS IN PATIENTS OF GENERAL MEDICINE, ICU and EMERGENCY DEPARTMENTS AT A TERTIARY CARE HOSPITAL

Objective: To evaluate the drug-drug interactions in General medicine, ICU and Emergency departments.Methods: It is a prospective-observational study. This study included hospital In-patients treated in General medicine, ICU and Emergency. Data were collected from the medical records of In-patients which includes patient’s demographic details, medical history, social history, treatment chart, status and drug-drug interaction is assessed by using Lexicompand Medscape and other tertiary resources and documented in a suitably designed data collection form.Results: A total of 250 subjects were enrolled in the study. The majority (23.6%) of cases were identified in the age group 51–60 y old. Higher rate of DDIs was identified in the male gender prescriptions. 70% moderate interactions, 33.6% Minor interactions, 6.4% serious interaction found in General medicine, ICU and Emergency departments.Conclusion: Polypharmacy, age and comorbid condition were took part major role in drug-drug interactions.