Open AccessA REVIEW ON CURRENT SCENARIO OF ORAL CANCER IN INDIA WITH SPECIAL EMPHASIS ON MODERN DETECTION SYSTEMS AND BIOMARKERS
Author(s) -
Jeevitaa Kshersagar,
Poonam Bedge,
Rakhi V Jagdale,
Yashwant Toro,
Shimpa Sharma,
Meghnad Joshi
Publication year - 2020
Publication title -
international journal of applied pharmaceutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.238
H-Index - 15
ISSN - 0975-7058
DOI - 10.22159/ijap.2020.v12s4.40098
Subject(s) - medicine , intensive care medicine , oral cancers , cancer , basal cell , population , dermatology , pathology , environmental health
Oral squamous cell carcinoma is a major public health concern worldwide and a growing threat for rapidly developing economies such as India, where it ranks among the top three cancers. This review aims to discuss the national status of oral cancer in terms of incidences and mortality. We have added the emphasis on clinical characteristics of oral potentially malignant disorders and emerging optical diagnostic techniques to detect oral lesions which would otherwise go undetected by a conventional oral examination. Modern detection systems such as autofluorescence, chemiluminiscence, Narrowband imaging and Raman spectroscopy will definitely aid Conventional oral examination for diagnosis. Definitive diagnosis of oral cancer by using saliva and serum-based noninvasive biomarkers can minimize the need of tissue biopsies and patient discomfort. Urgent research efforts are required to find new ways to identify and examine high-risk population for the early diagnosis and prevention of Oral squamous cell carcinoma.