Open AccessSUPERCRITICAL CARBON DIOXIDE EXTRACTION OF MANGO GINGER (CURCUMA MANGGA ROXB.): PROCESS OPTIMIZATION USING TAGUCHI METHOD
Author(s) -
Rinaldi Salea,
Erwan Y. Darussalam,
Stevanus Hiendrawan,
Bambang Veriansyah,
Raymond R. Tjandrawinata
Publication year - 2019
Publication title -
international journal of applied pharmaceutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.238
H-Index - 15
ISSN - 0975-7058
DOI - 10.22159/ijap.2019v11i2.31079
Subject(s) - taguchi methods , supercritical carbon dioxide , extraction (chemistry) , yield (engineering) , chromatography , volumetric flow rate , curcuma , supercritical fluid , supercritical fluid extraction , materials science , carbon dioxide , chemistry , medicine , composite material , traditional medicine , organic chemistry , physics , quantum mechanics
Objective: Extraction of Curcuma mangga (C. mangga) using supercritical carbon dioxide (SC-CO2) was investigated to provide information about the optimum extraction condition.
Methods: A Taguchi method with L9 orthogonal array design was used to determine the optimum extraction conditions. Effects of extraction pressure, temperature, CO2 flow rate and dynamic extraction time on C. mangga oil yield were investigated at levels ranging between 150-350 bar, 40-60 °C, 10-20 g/min and 120-240 min, respectively.
Results: The highest C. mangga oil yield (5.223%) from SC-CO2 extraction was obtained at a pressure of 350 bar, temperature of 60 °C, CO2 flow rate of 20 g/min and dynamic extraction time of 240 min. The experimental C. mangga oil yield at optimum condition was in a good agreement with the values predicted by computational process using Taguchi method. Based on S/N ratio calculation, the most influencing parameters in maximizing C. mangga oil yield is extraction temperature, followed by extraction pressure, dynamic extraction time and CO2 flow rate.
Conclusion: In this study, Taguchi method was successfully applied to optimize SC-CO2 extraction of C. mangga. Taguchi method was able to simplify the experimental procedure of SC-CO2 extraction.