Open AccessBIOLOGICAL ACTIVITY OF ß-GLUCANS FROM EDIBLE MUSHROOM, SCHIZOPHYLLUM COMMUNE IN THAILAND
Author(s) -
Samraj Rattanadilok Na Phuket,
Titima Sangkaew,
Piyatida Chanapan,
Surachai Techaoei
Publication year - 2019
Publication title -
international journal of applied pharmaceutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.238
H-Index - 15
ISSN - 0975-7058
DOI - 10.22159/ijap.2019.v11s5.t0083
Subject(s) - schizophyllum commune , dpph , chemistry , abts , mushroom , antioxidant , food science , edible mushroom , traditional medicine , organic chemistry , biochemistry , medicine
Objective: The objective of this research was to determine the antioxidant of ß-glucans from an edible mushroom, Schizophyllum commune in Thailand.Methods: The antioxidant activity of ß-glucans was measured in terms of hydrogen donating or radical scavenging ability by 2, 2-diphenyl-1-picrylhydrazyl (DPPH) method,2,2´-azinobis-(3-ethyl-benzothiazoline-6-sulfonic acid (ABTS) radical scavenging activity analysis, and total phenoliccompounds. The ß-glucans structure was analyzed using Fourier-transform infrared spectrophotometer.Results: The ß-glucans were extracted from S. commune and tested biological activities. Using the Folin–Ciocalteu Reactive method, we found thatthe phenolic compound contents of ethanol extracts of the mushroom sample were 284.41±1.22 mgGAE/g extract. The IC50 radical scavenging ability(DPPH) and IC50 radical scavenging activity (ABTS) of ß-glucans were 0.829±0.006 and 0.724±0.021 mg/mL, respectively.Conclusion: The ß-glucans from S. commune in Thailand showed a potent antioxidant activity and it will be able to apply in pharmaceutical cosmetics.