Open AccessEFFECT OF HERBAL TOOTHPASTE CONTAINING NEEM LEAVES EXTRACT (AZADIRACHTA INDICA) AGAINST GINGIVITIS: A CLINICAL STUDY
Author(s) -
Amelia Priscilla Sugiarta,
Robert Lessang,
. Natalina
Publication year - 2019
Publication title -
international journal of applied pharmaceutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.238
H-Index - 15
ISSN - 0975-7058
DOI - 10.22159/ijap.2019.v11s1.ar173
Subject(s) - azadirachta , toothpaste , gingivitis , antiseptic , aloe vera , traditional medicine , medicine , meliaceae , ocimum , dentistry , neem oil , toxicology , biology , pathology
Objective: Neem leaves are known to have antibacterial, anti-inflammatory, antifungal, antiseptic, antitumor, antihyperglycemic, antiulcer, andantiviral effects. In addition, they can reduce the counts of plaque-forming bacteria in the oral cavity. This study aimed to evaluate the effect of anherbal toothpaste containing neem leaves extract against gingivitis.Methods: A total of 40 subjects were divided into two groups (n=20 each): Experimental and control. Those in the test group were instructed to brushtheir teeth twice a day for 7 days with neem leaves extract toothpaste, whereas the control group subjects were asked to continue with the non-herbalpaste they used for tooth brushing. Plaque index (PI) and papillary bleeding index (PBI) were measured on day 0 and day 7.Results: Significant reductions in PI and PBI were noted between the test and control groups.Conclusion: The findings of this clinical study provide evidence that neem leaf extracts are effective in reducing gingivitis.