Open AccessEFFECTIVENESS OF IDENTIFIED JAVANESE TURMERIC ETHANOL EXTRACT FOR THE INHIBITION OF BIOFILM FORMATION BY STREPTOCOCCUS MUTANS AND PORPHYROMONAS GINGIVALIS
Author(s) -
Liza Noah Febriana Marpaung,
Dewi Fatma Suniarti,
Agoeng Tjahajani Sarwono
Publication year - 2019
Publication title -
international journal of applied pharmaceutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.238
H-Index - 15
ISSN - 0975-7058
DOI - 10.22159/ijap.2019.v11s1.156
Subject(s) - biofilm , porphyromonas gingivalis , streptococcus mutans , crystal violet , microbiology and biotechnology , chemistry , minimum inhibitory concentration , minimum bactericidal concentration , broth microdilution , antimicrobial , bacteria , biology , genetics
Objective: To study the effectiveness of identified Javanese turmeric ethanol extract (IJTEE) against single and combined biofilm formation byStreptococcus mutans and Porphyromonas gingivalis.Methods: S. mutans ATCC 25175 and P. gingivalis ATCC 33277 were tested for the minimum inhibitory concentration (MIC) and minimum bactericidalconcentration (MBC) of IJTEE using microdilution technique. The inhibition of biofilm formation by IJTEE was analyzed using crystal violet assay.Results: MIC and MBC of IJTEE for S. mutans were 5% and 15%, respectively. MIC of IJTEE for the biofilm of S. mutans was 1% and for that ofP. gingivalis was 15%; the MIC of IJTEE for the combined biofilm was 0.5%.Conclusion: IJTEE was effective in inhibiting single and combined biofilm formation by S. mutans and P. gingivalis.