Open AccessSYNTHESIS AND ANALYSIS OF ZINC-METHIONINE, ZINC-TRYPTOPHAN, COPPER-LYSINE, AND COPPER-ISOLEUCINE COMPLEXES USING ATOMIC ABSORPTION SPECTROPHOTOMETRY
Author(s) -
Nadhila Adani Koppa,
Harmita,
Catur Jatmika
Publication year - 2018
Publication title -
international journal of applied pharmaceutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.238
H-Index - 15
ISSN - 0975-7058
DOI - 10.22159/ijap.2018.v10s1.92
Subject(s) - zinc , chemistry , copper , atomic absorption spectroscopy , isoleucine , spectrophotometry , methionine , metal , fourier transform infrared spectroscopy , amino acid , tryptophan , nuclear chemistry , inorganic chemistry , lysine , absorption (acoustics) , chromatography , leucine , organic chemistry , biochemistry , materials science , physics , quantum mechanics , composite material
Objective: This study aimed to synthesize an organic form of Zn and Cu to then produce metal complexes with amino acids, as well as to analyze thefree and bound metal content of the complexes.Methods: In this study, the synthesis methods for zinc-methionine (Zn(Met)2), zinc-tryptophan (ZnTrp), copper-lysine (Cu(Lys)2), and copperisoleucine(Cu(Ile)2) complexes were based on previous studies. Sample verification was conducted using Fourier transform infrared spectroscopy,which can determine the stretched spectra produced by the complexes. In addition, atomic absorption spectrophotometry was used to analyze themetal content of the complexes.Results: The yields gained from the synthesis of Zn(Met)2, ZnTrp, Cu(Lys)2, and Cu(Ile)2 complexes were 95.99%, 94.18%, 91.89%, and 95.73%,respectively, with a maximum metal content of 199.51, 246.98, 176.99, and 189.75 mg/g, respectively.Conclusion: The mineral concentration of each complex differed, depending on the type of mineral and ligand.