Open AccessWOUND HEALING ACTIVITY OF LEMON PEPPER ESSENTIAL OIL IN BURN WOUND OF WISTAR RAT
Author(s) -
Purnama Dewi,
Chrismis Novalinda Ginting,
Linda Chiuman,
Adrian Khu
Publication year - 2021
Publication title -
asian journal of pharmaceutical and clinical research
Language(s) - English
Resource type - Journals
eISSN - 2455-3891
pISSN - 0974-2441
DOI - 10.22159/ajpcr.2021.v14i5.41598
Subject(s) - pepper , wound healing , significant difference , burn wound , medicine , traditional medicine , essential oil , horticulture , surgery , chemistry , biology , food science
Objective: The purpose of the study was to investigate the acceleration of the wound healing properties from lemon pepper’s essential oil as the lemon pepper’s ointment.
Methods: There were 20 Wistar rats as an animal trial divided into four sample groups, including control (ointment base), standard (Nebacetin®), 5% lemon pepper, and 10% lemon pepper ointment, and all groups were injured by electric soldier for 10 s. The wound contraction and epithelialization period were the parameters of wound healing activity.
Result: Wound contraction as the parameter of wound healing showed significant difference between the standard and lemon pepper ointment (p 0.05).
Conclusion: It can be concluded that the lemon pepper ointment had the potential to accelerate wound healing activity.