Open AccessA PROSPECTIVE OBSERVATIONAL STUDY ON THE INCIDENCE OF DRUG-RELATED HOSPITAL ADMISSIONS IN A TERTIARY CARE HOSPITAL
Author(s) -
Akshay Tl,
Alaka Prakash,
Ashiq Mohamed Anas M,
S Diwahar,
P. Rama
Publication year - 2021
Publication title -
asian journal of pharmaceutical and clinical research
Language(s) - English
Resource type - Journals
eISSN - 2455-3891
pISSN - 0974-2441
DOI - 10.22159/ajpcr.2021.v14i4.40444
Subject(s) - observational study , polypharmacy , medicine , incidence (geometry) , prospective cohort study , drug class , drug , emergency medicine , risk factor , pediatrics , pharmacology , physics , optics
Objectives: The objective of the study is to identify the incidence of drug-related problems coming to the EMD, classify, and identify the risk factor for DRP.
Methods: This was a prospective observational study conducted in the emergency department for a period of 6 months. The patients admitted through EMD with DRP were identified and then were classified according to Hepler and Strand, 1990 and Classen et al., 1997.
Results: A total of 109 patients were identified with DRP in our study. Among them, major part was contributed by ADRs (69.7%), non-adherence (27.5%) followed by sub-therapeutic dosage, and untreated indication and overdosage (0.91%). The major organ system involved in DRPs was found to be neurological system (26.60%) and gastrointestinal system (23.85%). The major causative drug class for DRP was found to be anti-thrombotic agents (27%), and the major risk factor for the development of DRP was found to be polypharmacy.
Conclusion: Drug-related problems are becoming one of the major reasons for the EMD admissions in the hospitals. It can cause significant burden to the society and to the health of the people.