Open AccessEFFICACY OF TERIPARATIDE IN COMMINUTED FRACTURE HEALING IN LOWER LIMB: A RETROSPECTIVE STUDY
Author(s) -
Sneh Dudhia,
Ketas Mahajan
Publication year - 2021
Publication title -
asian journal of pharmaceutical and clinical research
Language(s) - English
Resource type - Journals
eISSN - 2455-3891
pISSN - 0974-2441
DOI - 10.22159/ajpcr.2021.v14i11.43135
Subject(s) - teriparatide , medicine , bone healing , surgery , osteoporosis , group b , retrospective cohort study , dentistry , bone mineral
Objective: The objective of the study was to show the efficacy of teriparatide in comminuted fracture healing and improvement in overall functional recovery.Methods: A total of 30 subjects who suffered from comminuted fractures of lower limb were selected. Subjects were categorized into two groups: Group A (n=15) contained individuals with teriparatide administration and Group B (n=15) contained individuals who were not administered teriparatide. 20 mg of teriparatide was injected subcutaneously for a period of 3 months. Patients were followed up ay durations of 4, 8, and 12 weeks. Obtained data were entered into Microsoft Excel Worksheets and descriptive analysis was performed. Chi-square test was used to analyze all obtained data.Results: Among Group A patients, the fracture healing rates were found to be significantly earlier with comparison to control group (Group B).Conclusion: Teriparatide was observed to be effective in comminuted fracture healing and has demonstrated good clinical outcome.