Open AccessINHIBITION OF CALCIUM OXALATE CRYSTALLIZATION BY AN EXTRACT OF OCIMUM BASILICUM SEEDS: AN IN-VITRO STUDY
Author(s) -
PATEL RAVINDRAKUMAR K,
PATEL SANDIP B
Publication year - 2020
Publication title -
asian journal of pharmaceutical and clinical research
Language(s) - English
Resource type - Journals
eISSN - 2455-3891
pISSN - 0974-2441
DOI - 10.22159/ajpcr.2020.v13i9.37926
Subject(s) - basilicum , ocimum , calcium oxalate , crystalluria , traditional medicine , crystallization , urinary system , calcium oxalate crystals , chemistry , herb , calcium , medicine , pharmacology , medicinal herbs , organic chemistry
Objective: Ocimum basilicum (OB) has been used to treat diverse illnesses which include urinary stone disorder for a reason that historical time in India. We investigated OB seeds for antiurolithic activity.
Methods: Calcium oxalate crystallization becomes triggered by the addition of 0.01 M sodium oxalate answers in normal human urine and nucleation was done.
Results: OB seeds were discovered to be robust and promising antiurolithiatic agents which are in accordance with its use in traditional medication.
Conclusion: An extract of the traditional herb OB has super inhibitory activity on crystalluria and therefore might be useful in dissolving urinary stone; however, in addition, a study in animal fashions of urolithiasis is needed to assess its capability antiurolithiatic interest.