Open AccessDIABETES MELLITUS TREATMENT: A RAPID REVIEW ON INNOVATIVE THERAPIES
Author(s) -
D. Krishna Veni,
Neha Gupta
Publication year - 2019
Publication title -
asian journal of pharmaceutical and clinical research
Language(s) - English
Resource type - Journals
eISSN - 2455-3891
pISSN - 0974-2441
DOI - 10.22159/ajpcr.2019.v12i1.28285
Subject(s) - medicine , diabetes mellitus , insulin , type 2 diabetes mellitus , transplantation , transdifferentiation , endocrinology , pharmacology , stem cell , biology , genetics
Diabetes mellitus is a chronic and metabolic disorder which results from defects in a section of insulin, action of insulin, or both. Primarily drugs are used to control the symptoms and save life. Secondary aims are to prevent long-term diabetic complications and by eliminating various risk factors to increase longevity. In type I diabetes mellitus, new innovative therapies such as pancreatic transplantation, pancreatic islet transplantation, stem cell therapy, transdifferentiation, and gene therapy are discussed, and regarding type II diabetes mellitus, treatment is based on drugs which stimulates the secretion of insulin such as conventional therapy, antihypoglycemic agents such as insulin, insulin secretagogues, and insulin sensitizers, α-glucosidase inhibitors, dipeptidyl peptidase-4 inhibitors, and sodium-glucose cotransporter 2 inhibitors, and a list of patents for the treatment of diabetes mellitus are discussed in this review article.