Open AccessSYNTHESIS OF SOME NOVEL PYRAZOLE DERIVATIVES AND EVALUATION OF THEIR PURIFICATION OF CHROMATOGRAPHY IN THIN-LAYER CHROMATOGRAPHY
Author(s) -
B Swapna,
Vijey Aanandhi M
Publication year - 2018
Publication title -
asian journal of pharmaceutical and clinical research
Language(s) - English
Resource type - Journals
eISSN - 2455-3891
pISSN - 0974-2441
DOI - 10.22159/ajpcr.2018.v11s4.31678
Subject(s) - pyrazole , pyrimidine , solubility , chemistry , thin layer chromatography , chromatography , characterization (materials science) , combinatorial chemistry , materials science , organic chemistry , nanotechnology , stereochemistry
Objective: The main objective of the study is to synthesis some novel pyrimidine scaffold which has wide range of properties of biological activities.Methods: Synthesis of different pyrazole derivatives compounds identification and characterization (M.P, solubility, Rf values, and spectral studies). The present work was characterized by infrared, nuclear magnetic resonance, and mass spectral analysis pharmacological evaluation.Results: Identification and characterization (M.P, solubility, Rf values and spectral studies) are carried out.