Open AccessTHE EFFECTS OF THE ADDUCTION OF EFFERVESCENT POWDER OF BASTARD CEDAR LEAF (GUAZUMA ULMIFOLIA LAMK.) EXTRACT TOWARD WEIGHT REDUCTION OF MALE MICE
Author(s) -
Sumaiyah Sumaiyah,
Rizky Triandini,
Aminah Dalimunthe
Publication year - 2018
Publication title -
asian journal of pharmaceutical and clinical research
Language(s) - English
Resource type - Journals
eISSN - 2455-3891
pISSN - 0974-2441
DOI - 10.22159/ajpcr.2018.v11s1.26604
Subject(s) - body weight , zoology , dosage form , traditional medicine , medicine , pharmacology , biology
Objective: The objective of this study was to discover the effect of the adduction of Bastard cedar leaf extract that was formulated in the form of effervescent powder toward weight loss.Methods: The study design was an experimental study with pretest–posttest one group control design. The sample was divided into 3 treatment groups which were dosage 1 g/kg body weight (BW), 2 g/kg BW, and 3 g/kg BW of Bastard cedar leaf effervescent powder and one control group. The research was conducted for 28 days.Result: The result of the research exhibited the 1st day of the adduction of Bastard cedar leaf effervescent powder that the dosage 3 g/Kg BW contributed to the largest reduction compared with the others. On the last day of adduction, dosage 1 g/Kg BW contributed almost the similar weight reduction effect to the mouse with the dosage 3 g/Kg BW; however, when both were compared, the dosage 3 g/Kg BW remained giving the most significant effect (p<0.05).Conclusion: The adduction of bastard cedar leaf effervescent powder could reduce the weight of the mouse in all dosage treatment which was dosage 1 g/Kg BW, 2 g/Kg BW, and 3 g/Kg BW.