
THE INFLUENCE OF RED FRUIT (PANDANUS CONOIDEUS LAM.) OIL ON GLUTATHIONE PEROXIDASE LEVEL AT MAXIMUM PHYSICAL ACTIVITY
Author(s) -
Fajar Apollo Sinaga,
Nora Susanti
Publication year - 2018
Publication title -
asian journal of pharmaceutical and clinical research
Language(s) - English
Resource type - Journals
eISSN - 2455-3891
pISSN - 0974-2441
DOI - 10.22159/ajpcr.2018.v11s1.26579
Subject(s) - glutathione peroxidase , chemistry , analysis of variance , peroxidase , zoology , glutathione , medicine , biochemistry , biology , enzyme
Objectives: This study aims to see the effect of red fruit oil (RFO) on glutathione peroxidase (GPx) level at maximum physical activity.Methods: This study is an experimental research using the design of randomized control group pretest-posttest. This study was using 24 male mice divided into four groups, the control group was given aquadest, the treatment groups P1, P2, and P3 were given the RFO orally of 0.15 ml/kg BW, 0.3 ml/kg BW, and 0.6 ml/kg BW, respectively, for a month. The level of GPx was checked for all groups at the beginning of study and after the maximum physical activity. The obtained data were then tested statistically using t-test and ANOVA.Results: The result shows the RFO supplementation during exercise increased the GPx level in P1, P2, and P3 groups with p<0.05, and the higher RFO dosage resulted in higher GPx level at p<0.05.Conclusion: The conclusion of this study is the RFO could increase the level of GPx at maximum physical activity.