Open AccessMICRO RAMAN SPECTROSCOPIC ANALYSIS ON BLOOD SERUM SAMPLES OF DUCTAL CARCINOMA PATIENTS
Author(s) -
Sanoj Varghese,
Ambili Reveendran,
V. Senthil Kumar,
Karthikeyan Tm,
Venkiteshan Ranganathan
Publication year - 2018
Publication title -
asian journal of pharmaceutical and clinical research
Language(s) - English
Resource type - Journals
eISSN - 2455-3891
pISSN - 0974-2441
DOI - 10.22159/ajpcr.2018.v11i9.26806
Subject(s) - raman spectroscopy , human breast , breast cancer , analytical chemistry (journal) , ductal carcinoma , cancer , chemistry , medicine , nuclear magnetic resonance , materials science , chromatography , pathology , optics , physics
Objective: Identification of biochemical changes in ductal cancer patient’s serum samples using micro Raman spectroscopy.Methods: Micro Raman spectroscopy was used for the identification of Raman shift bands. Data analysis was done using K-means clustering.Results: Micro Raman spectroscopic analysis of human breast cancer patient’s serum samples was done. Biochemicals present in the samples were identified from the peak evaluations. K-means clustering analysis was used to differentiate the biochemicals present in the samples.Conclusion: From the study, we conclude that Raman spectroscopy has the potential to differentiate the biochemical changes occurring in the human body, and the differentiation can be done using K-means clustering.