Open AccessENVIRONMENTAL EXPOSURES TO LOW LEVEL OF CADMIUM AND LEAD AND HEARING IMPAIRMENT IN IRAQI PATIENTS
Author(s) -
Wrood S. Al-khfajy,
Ghadeer Kadhum Baiee,
Inam Sameh Arif
Publication year - 2018
Publication title -
asian journal of pharmaceutical and clinical research
Language(s) - English
Resource type - Journals
eISSN - 2455-3891
pISSN - 0974-2441
DOI - 10.22159/ajpcr.2018.v11i7.26235
Subject(s) - pure tone audiometry , cadmium , medicine , audiology , lead (geology) , blood lead level , hearing loss , cadmium exposure , audiometry , lead exposure , toxicity , chemistry , biology , cats , paleontology , organic chemistry
Objectives: We examined the relations between blood cadmium and lead exposure and hearing impairments in the Iraqi people.Methods: We analyzed data from 51 individual 13–75 ages who had been randomly dispensed to the audiometry examination center at Al-Hilla Teaching Hospital (Babel) for each Iraqi civilian who said, “I suffering from the hearing problem.” Pure-tone average (PTA) of auditory thresholds at frequencies of 0.5, 1, 2, and 4 kHz was calculated, and hearing impairment was described as a PTA >25 dB in either ear.Results: All patients who suffer from hearing impairment have serum lead level (23.14±1.76 μg/dL), which is a significantly elevated in comparison to control group (21.20±2.08 μg/dL). In addition to lead, the blood level of cadmium in people with hearing impairment was showed a significant elevation (0.28±0.05 μg/dL) in comparison to normal people (0.22±0.03 μg/dL). In general, this elevation remains within normal reference for the blood level of cadmium (0.5 μg/dL).Conclusions: The present study revealed that the environmental and occupational cadmium and lead coexposures lead to a significant elevation in the blood level of these metals and could have an essential part in the progression of hearing loss.