Open AccessIN VITRO STUDIES ON ANTIOXIDANT AND ANTIDIABETIC ACTIVITY OF PLEUROTUS EOUS MUSHROOM IN METHANOL AND AQUEOUS EXTRACT
Author(s) -
K Shoba,
S Krishnakumari
Publication year - 2018
Publication title -
asian journal of pharmaceutical and clinical research
Language(s) - English
Resource type - Journals
eISSN - 2455-3891
pISSN - 0974-2441
DOI - 10.22159/ajpcr.2018.v11i5.22828
Subject(s) - antioxidant , mushroom , hydrogen peroxide , chemistry , pleurotus , hydroxyl radical , methanol , amylase , ic50 , aqueous solution , in vitro , food science , traditional medicine , biochemistry , organic chemistry , enzyme , medicine
Objective: The present study evaluates the antioxidant and antidiabetic activity of the mushroom.Methods: Antioxidant activity was evaluated using hydroxyl radical, hydrogen peroxide, and antidiabetic activity using α-amylase and α-glucosidase.Result: The antioxidant IC50 for the mushroom extracts methanol and aqueous(Hydroxyl radical) was found to be 290,440μg/ml (Hydrogen peroxide) 475,370 μg/ml and antidiabetic(α Amylase) IC50 was found to be 460,500 μg/ml and (α Glucosidase) 325,280 μg/ml respectively.Conclusion: The result obtained in the in vitro methods suggests that Pleurotus eous mushroom can be administered for its antioxidant and antidiabetic activity