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open-access-imgOpen AccessEVALUATION OF IN VITRO ANTHELMINTIC PROPERTIES OF AVICENNIA MARINA LEAVES
Author(s)
Gana Manjusha Kondepudi
Publication year2018
Publication title
asian journal of pharmaceutical and clinical research
Resource typeJournals
PublisherInnovare Academic Sciences
 Objectives: The purpose of the present study was to determine the anthelmintic properties of chloroform, methanol and aqueous extracts of Avicennia marina leaves on Indian earthworm- Pheretima posthuma. Methods: Three concentrations of each extract (25 mg/ml, 50 mg/ml, and 75 mg/ml) were studied in this activity to determine the time of paralysis (vermifuge) and the time of the death of the worms (vermicidal). Piperazine citrate in the same concentrations was taken a reference standard and normal water was taken as control. The time taken for paralysis and death of the worms was recorded.Results: All the extracts showed dose-dependent and a significant activity was shown at higher concentration (75 mg/ml). Methanolic extract showed peak activity at a concentration of 75 mg/ml.Conclusion: Based on the results it was found that the leaves of A. marina possess vermifuge and vermicidal activities and can be used as an effective anthelmintic.
Subject(s)anthelmintic , avicennia marina , biology , chemistry , ecology , fishery , mangrove , medicine , toxicology , traditional medicine
Language(s)English
ISSN0974-2441
DOI10.22159/ajpcr.2018.v11i4.23605

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