Open AccessPOTENCY OF CHIVES (ALLIUM SCHOENOPRASUM L.) LEAVES INFUSE AS INHIBITOR CALCIUM LITHOGENESIS ON URINARY TRACT
Author(s) -
Siti Morin Sinaga,
Iksen Iksen,
Ginda Haro,
Selvy Wardhany
Publication year - 2018
Publication title -
asian journal of pharmaceutical and clinical research
Language(s) - English
Resource type - Journals
eISSN - 2455-3891
pISSN - 0974-2441
DOI - 10.22159/ajpcr.2018.v11i3.22851
Subject(s) - phytochemical , allium , calcium , potency , in vitro , biology , botany , traditional medicine , chemistry , biochemistry , medicine , organic chemistry
Objective: This study examined the antilithogenesis activity by in vitro and histopathologic study from the infuse solution of chives leaves powder.Methods: The study begins with standard phytochemical screening on the powder of chives leaves. For performing in vitro antilithogenesis activity, atomic absorption spectrophotometry method was adopted to measure the dissolved calcium level. Histopathologic study was using animal models.Result: Phytochemical screening of chives leaves powder has a lot of phytochemical constituents. In vitro assay showed that chives infuse can dissolve the human calcium stone (47.7% for 12.5% concentration of chives leaves infuse). The histopathologic study showed that chives leaves can be used to treat the calcium lithogenesis.Conclusion: This experiment provides evidence that chives leaves have highlighted the potential efficacy for the treatment of calcium lithogenesis.