Open AccessCARBAMAZEPINE-INDUCED TOXIC EPIDERMAL NECROLYSIS: A CASE REPORT
Author(s) -
Sherin Alexander,
Devayani Santhu,
T Narendran,
Julie Mariam Joshua,
Meenu Vijayan,
Jacob Thomas
Publication year - 2018
Publication title -
asian journal of pharmaceutical and clinical research
Language(s) - English
Resource type - Journals
eISSN - 2455-3891
pISSN - 0974-2441
DOI - 10.22159/ajpcr.2018.v11i12.28294
Subject(s) - carbamazepine , toxic epidermal necrolysis , lamotrigine , phenytoin , allopurinol , medicine , sepsis , dermatology , nonsteroidal , pharmacology , epilepsy , immunology , psychiatry
Toxic epidermal necrolysis (TEN) is a life-threatening dermatological disorder characterized by erythematous lesions, necrosis, exfoliation, sepsis, and death. This may be due to different reasons such as chemical exposure, systemic infections, or some reactions of drugs such as carbamazepine, phenytoin, allopurinol, lamotrigine, and nonsteroidal anti-inflammatory drugs. In this case, the patient was on carbamazepine for the management of alcohol withdrawal symptoms. Moreover, this might be the reason for the occurrence of TEN. For his condition, he had given corticosteroids, antibiotics for sepsis, and other supportive measures.