Open AccessSTUDY OF THE IMPACT OF MICRONUTRIENT FOUND IN SPERAMAX® DURING PREGNANCY PERIODS ON EMBRYONIC DEVELOPMENT AND NEWBORN
Author(s) -
Sawsan S. Hamzah
Publication year - 2018
Publication title -
asian journal of pharmaceutical and clinical research
Language(s) - English
Resource type - Journals
eISSN - 2455-3891
pISSN - 0974-2441
DOI - 10.22159/ajpcr.2018.v11i10.26780
Subject(s) - micronutrient , pregnancy , medicine , physiology , adverse effect , nutritional supplementation , group b , zoology , obstetrics , gynecology , biology , genetics , pathology
Objective: This paper aims at evaluating the benefits of vitamins and minerals found in the Speramax® supplement and the risks to mother and infants of additional supplementation and possible adverse interactions between micronutrients in pregnancy.Method: A total of 30 male and 120 female albinos Swiss mice of 8–12 weeks of age weighing 25–35 g were used. Speramax was administrated orally for 1, 2, and 4 weeks. Fertile female mice were classified into four main groups: Group 1 is spontaneously (SPO); Group 2 is administrated with SperamaxÒ only; Group 3 is treated SperamaxÒ with superovulation (SUO); and Group 4 is superovulated only without Speramax.Result: The results indicated that treatment with Speramax® showed a positive effect on neonatal development and an increase in the number of newborn SPO and SUO treated with Speramax® after 1 week and 2 weeks. The results showed high significance (p˂0.000) compared with SPO and SUO mice not treated with Speramax® and with groups treated for 4 weeks.Conclusion: Good nutrition found in Speramax® may, therefore, be especially important to this group of infants and must be instituted alongside other nutritional supplements.