Open AccessL-ASPARAGINASE INDUCED HYPOFIBRINOGENEMIA: A CASE REPORT
Author(s) -
Balaji Ommurugan,
Amita Priya,
Navin Patil
Publication year - 2017
Publication title -
asian journal of pharmaceutical and clinical research
Language(s) - English
Resource type - Journals
eISSN - 2455-3891
pISSN - 0974-2441
DOI - 10.22159/ajpcr.2017.v10i5.17320
Subject(s) - hypofibrinogenemia , asparaginase , leukemia , medicine , lymphoblastic leukemia , adverse effect , pharmacology , fibrinogen
Anticancer therapy is always known to cause various side effects. L-asparaginase used in the treatment of adult T-cell lymphoblastic leukemia is anovel class of drug, an enzyme produced from plants as well as microorganisms except human. It is known to cause various adverse reactions including life-threatening neurological complications and thrombotic disorders. Hence, we report a case of hypofibrinogenemia associated with L-asparaginase in a patient treated for T-cell adult lymphoblastic leukemia.Keywords: L-asparaginase, Hypofibrinogenemia, Adverse effect, Leukemia.