Open AccessANTIBACTERIAL ACTIVITY OF AQUEOUS ALCOHOLIC EXTRACT OF ABUTILON INDICUM AERIAL PARTS AGAINST E .FAECALIS – AN INVITRO STUDY
Author(s) -
Jannathul Feridoz,
R. Anitha
Publication year - 2017
Publication title -
asian journal of pharmaceutical and clinical research
Language(s) - English
Resource type - Journals
eISSN - 2455-3891
pISSN - 0974-2441
DOI - 10.22159/ajpcr.2017.v10i5.15636
Subject(s) - enterococcus faecalis , antibacterial activity , chemistry , agar diffusion test , root canal , traditional medicine , agar plate , ethyl acetate , chromatography , microbiology and biotechnology , biology , bacteria , biochemistry , escherichia coli , medicine , genetics , gene , dentistry
Objective: To evaluate the antibacterial activity of the aqueous alcoholic extracts of Abutilon indicum aerial parts against Enterococcus faecalis.Methods: Agar well diffusion assay, as well as microbroth dilution assays, were used for determination of antibacterial activity. The assay was done intriplicate, and chlorhexidine 0.2% was used as the control.Results: Different concentrations (200, 400, and 800 mg/mL) of the ethyl acetate extract of A. indicum aerial parts showed dose-dependantantibacterial activity. The maximum zone of inhibition was 30 mm at the maximum concentration used (800 mg/mL), and the minimum inhibitoryconcentration/minimum bactericidal concentration was found to be 200 mg/mL.Conclusion: This study suggests that the aqueous alcoholic extract of A. indicum aerial parts contains promising antibacterial substances which arehaving activity against E. faecalis. E. faecalis being one of the major threats for root canal failure during endodontic treatment; plants with antibacterialactivity against E. faecalis will be promising.Keywords: Abutilon indicum, Enterococcus faecalis, Antibacterial activity, Root canal failure.