Open AccessEVALUATION OF ANTIOXIDANT AND ANTI-INFLAMMATORY PROPERTIES OF AQUEOUS EXTRACT OF WILD MUSHROOMS COLLECTED FROM HIMACHAL PRADESH
Author(s) -
Aarti Bains,
Astha Tripathi
Publication year - 2017
Publication title -
asian journal of pharmaceutical and clinical research
Language(s) - English
Resource type - Journals
eISSN - 2455-3891
pISSN - 0974-2441
DOI - 10.22159/ajpcr.2017.v10i3.16547
Subject(s) - phytochemical , antioxidant , ascorbic acid , chemistry , food science , traditional medicine , phenol , flavonoid , mushroom , oxidative stress , carotenoid , biochemistry , medicine , organic chemistry
Objective: The objective of this study is to elucidate phytochemical contents, antioxidant, and anti-inflammatory activity of wild mushrooms collectedfrom Himachal Pradesh.Methods: Quantitative analysis of phytochemical constituents was carried out using standard methods while 1,1 diphenylpicrylhydrazyl nitric oxide,hydrogen peroxide-free radical scavenging assay were used to evaluate the antioxidant properties of selected wild mushrooms. Anti-inflammatorycapacity of samples was evaluated by human red blood cell membrane stabilization and albumin denaturation inhibition method.Results: The results obtained revealed that Pleurotus floridanus showed higher total phenol, flavonoid carotenoid, and ascorbic acid contentsof 61.13±2.3 mg/g, 15.2±1.13 mg/g, 12.42±0.42 μg/g, 17.36±0.40 μg/g, and 14.55±0.58 mg/g. All the species showed antioxidant potential, butP. floridanus proved to be more active while Macrocybe sp. proved to be least one.Conclusion: The mushroom species analyzed have been showed to be good source of phytoconstituents, antioxidants, and also possess antiinflammatoryproperties, thus can be used in the management of oxidative stress-induced disease.Keywords: Wild mushrooms, Scavenging effect, Total phenol, Antioxidant, Anti-inflammatory.