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ANTIMICROBIAL AND ANTICANCER ACTIVITY OF SILVER NANOPARTICLES FROM EDIBLE MUSHROOM: A REVIEW
Author(s) -
Priyadarshni Karuppiah Chandran,
Mahalingam Pambayan Ulagan
Publication year - 2017
Publication title -
asian journal of pharmaceutical and clinical research
Language(s) - English
Resource type - Journals
eISSN - 2455-3891
pISSN - 0974-2441
DOI - 10.22159/ajpcr.2017.v10i3.16027
Subject(s) - antimicrobial , silver nanoparticle , silver nitrate , nanoparticle , mushroom , nanotechnology , nuclear chemistry , materials science , fourier transform infrared spectroscopy , chemistry , chemical engineering , organic chemistry , food science , engineering
Biologically inspired nanoparticle synthesis is currently a rapid expanding area of research in nanotechnology. Nanoparticle synthesis utilizing thebioresources such as plants and microbes appears to be a viable, low-cost, and eco-friendly approach. Especially mushrooms can be used for largescalesynthesis of silver nanoparticles as mushroom produces many proteins that reduce the silver nitrate during the biosynthesis. Silver nanoparticlescan be characterized using ultraviolet-visible (UV-VIS) spectroscopy, fourier transform infrared spectroscopy, X-ray diffraction, scanning electronmicroscopy, energy dispersive X-ray, and transmission electron microscope. Silver nanoparticles possess high antibacterial activity since silver indifferent forms has been extensively used as a medicine for curing diseases and promote wound healing. Silver nanoparticles have high surfacespecific area, which will lead to excellent antimicrobial activity as compared with bulk metallic silver. Further, the silver nanoparticles show anticanceractivity against various cell lines such as human epidermoid larynx carcinoma (HEP-2), colon adenocarcinoma (HCT-116), breast adenocarcinoma(MCF-7), liver carcinoma (Hep-G2), and intestinal adenocarcinoma (Caco2) were well documented. This review intends to present green synthesis ofsilver nanoparticles and their application as antimicrobial and anticancer agents.Keywords: Silver nanoparticles, Bioresources, Mushroom, Antimicrobial activity, Anticancer property.

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