Open AccessSTUDIES ON BIOACTIVE POTENTIAL OF STREPTOMYCES SPP. (KX710212). ISOLATED FROM ENVIRONMENTAL POLLUTED SAMPLE, RANIPET, VELLORE, INDIA
Author(s) -
N Henita Geo,
A. Panneerselvam
Publication year - 2016
Publication title -
asian journal of pharmaceutical and clinical research
Language(s) - English
Resource type - Journals
eISSN - 2455-3891
pISSN - 0974-2441
DOI - 10.22159/ajpcr.2016.v9s3.14788
Subject(s) - streptomyces , 16s ribosomal rna , biology , antibacterial activity , bacteria , traditional medicine , strain (injury) , microbiology and biotechnology , medicine , genetics , anatomy
Objective: Natural products from bacterial origin played and still play a valuable role in drug discovery and provide diverse health-promotingcompounds that help to cure or alleviate serious diseases.Methods: A total of 4 actinobacterial strains were isolated from 2 different environmental polluted soil samples collected from Ranipet, Vellore, TamilNadu, India. Of 15 isolates screened for antibacterial property, 4 isolates (PS1, PS2, and PS3) were found potent and characterized phenotypically andgenotypically.Results: The 16S rDNA gene sequences of potent strain showed 97% similarity with Streptomyces spp. and termed as Streptomyces sp. The bioactivitywas revealed by antibacterial and antioxidant activity.Conclusion: Hence, these findings provide scientific evidence to validate the pharmacological use and have the potential contribution in the discoveryof new lead that play a key role in the field of therapeutics.Keywords: Actinomycetes, Bioactive compounds, Antibacterial property.