Open AccessA CASE REPORT OF PHENYTOIN AND CARBAMAZEPINE CROSS-REACTIVITY
Author(s) -
Bhuvana Krishnaswamy,
N Sarala,
P N Venkatarathnamma,
Tarun Kumar
Publication year - 2016
Publication title -
asian journal of pharmaceutical and clinical research
Language(s) - English
Resource type - Journals
eISSN - 2455-3891
pISSN - 0974-2441
DOI - 10.22159/ajpcr.2016.v9s2.13599
Subject(s) - carbamazepine , phenytoin , reactivity (psychology) , anticonvulsant , medicine , pharmacology , anesthesia , epilepsy , psychiatry , pathology , alternative medicine
A case report of cross-reactivity between phenytoin and carbamazepine, a 63-year-old male patient was prescribed phenytoin for generalized seizures and on the 15 day of therapy developed generalized maculopapular eruptions. Phenytoin was discontinued, and carbamazepine was administered. After 28 days, he developed fever, generalized rashes with ulcers in the oral cavity. Carbamazepine was withdrawn, and the patient was treated symptomatically. th Keywords: Phenytoin, Carbamazepine, Cross-reactivity.