Open AccessMIDDLE EAR AND NASOPHARYNGEAL BACTERIAL FLORA AND THEIR SENSITIVITY IN ACTIVE STAGE OF MUCOSAL DISEASE OTITIS MEDIA: A COMPARISON
Author(s) -
Rakesh Vuppala,
Kathyayani Burugula,
R. Balakrishnan
Publication year - 2016
Publication title -
asian journal of pharmaceutical and clinical research
Language(s) - English
Resource type - Journals
eISSN - 2455-3891
pISSN - 0974-2441
DOI - 10.22159/ajpcr.2016.v9i5.13366
Subject(s) - medicine , otitis , moraxella catarrhalis , antibiotic sensitivity , middle ear , microbiological culture , microbiology and biotechnology , chronic suppurative otitis media , antibiotics , staphylococcus aureus , haemophilus influenzae , bacteria , surgery , biology , genetics
Objective: Identifying the role of nasopharyngeal bacteria in recurrent middle ear (ME) infection helps in developing an effective treatment strategy.We aimed to compare bacterial flora of ME with nasopharynx (NP) and their sensitivity patterns in active stage of mucosal disease - otitis media(CSOM).Methods: Ear and nasopharyngeal swabs from patients with active ear discharge for >3 months were processed for culture and sensitivity, theorganisms were identified using Gram-stain.Results: Twenty patients between 10 and 65 years and male:female ratio of 13:7 were enrolled. 9 had symptoms since childhood. 10 patientscomplained unilateral ear discharge; five each had discharge from the left and right ear. 11 patients had nasal symptoms; nose block due to obstruction(9), nasal discharge (8), and both symptoms were seen in eight patients. 14 patients (70.0%) had deviated nasal septum and 8 (40.0%) had dischargein the NP. Of 20 ear swabs, 19 grew bacteria; 1 was sterile (5.0%). 13 (65%) nasopharyngeal swabs grew bacteria, 7 were sterile. Culture yieldedaerobic bacteria. Staphylococcus aureus was the most common bacterium (9/20, 45.0%) followed by Pseudomonas (7/20, 35.0%) isolated from theear. The most common nasopharyngeal isolate was S. aureus (9=45%). 10 patients had common ME and nasopharyngeal flora. Organisms weresensitive to amoxicillin+clavulanic acid, fluoroquinolones. Sensitivity was observed to polymyxin, trimethoprim, and sulfamethoxazole also.Conclusion: Common ME and nasopharyngeal flora with same antibiotic sensitivity pattern suggest nasopharyngeal etiology. Nasopharyngeal floramay have a role in recurrent ME infections in mucosal disease - otitis media.Keywords: Bacterial flora, Bacterial sensitivity, mucosal disease otitis media, Pseudomonas aeruginosa, Staphylococcus aureus.