Open AccessPengaruh Material Konservasi Kolostrum terhadap Pelepasan Ion Ni
Author(s) -
Grahita Aditya,
Hikmah Nuraini,
Whinahyu Aji Sekarini
Publication year - 2019
Publication title -
jurnal teknosains: jurnal ilmiah sains dan teknologi/jurnal teknosains : jurnal ilmiah sains dan teknologi
Language(s) - English
Resource type - Journals
eISSN - 2443-1311
pISSN - 2089-6131
DOI - 10.22146/teknosains.37727
Subject(s) - colostrum , chemistry , potassium , saliva , sodium , inductively coupled plasma atomic emission spectroscopy , chromatography , nuclear chemistry , inductively coupled plasma , biochemistry , medicine , immunology , antibody , organic chemistry , physics , plasma , quantum mechanics
Nickel in orthodontic bracket will be released immediately in the oral cavity. The release of Ni ion may trigger type IV hypersensitivity reaction. Colostrum has a high content of lactoferrin which can inhibit T cells proliferation after nickel sensitization, and decrease oxidative stress. Adding potassium sorbat 0.5%, or fermentation of colostrum may extend colostrum storage. The purpose of this research is to know the difference of nickel ion release in colostrum with 0.5% potassium sorbat addition and fermented colostrum. Methods of the study were laboratory experimental with four groups, colostrum and 0.5% potassium sorbat, fermented colostrum, sodium fluoride and artificial saliva. The sample was incubated in 40°C for 7 days. Nickel ions was measured using an inductively coupled plasma-optical emission spectrophotometry (ICP-OES Perlun Elmer Optima 8300®). Ni ions release differences were tested using the Kruskall-Wallis and Mann Whitney test.The lowest rate of Ni ion release wasfound in the colostrum group with 0.5% potassium sorbat followed by the fermented colostrum group. Kruskal-Wallis test no significant difference (p> 0,05) in each study group. The Mann Whitney test found significant differences between colostrum solution with 0.5% potassium sorbat and sodium fluoride, and also artificial saliva. The results concluded that colostrum with 0.5% potassium sorbat inhibit the release of Ni ions.