Open AccessChemical Investigation and Antimicrobial Activity of Medicinal Plant <i>Toddalia asiatica</i> Lam
Author(s) -
Wilmar Maarisit,
Misran Lawani
Publication year - 2020
Publication title -
indonesian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.273
H-Index - 14
eISSN - 2460-1578
pISSN - 1411-9420
DOI - 10.22146/ijc.46643
Subject(s) - chemistry , antimicrobial , bacteria , traditional medicine , medicinal plants , fungus , gram , stereochemistry , botany , organic chemistry , biology , medicine , genetics
Medicinal plants have become important sources of natural products, which have been used in the development of therapeutic agents. Four new coumarins (1-4) have been isolated together with five known metabolites (5-9) from the medicinal plant T. asiatica. The structures of 1-9 were assigned based on their spectroscopic data. Compounds (1-9) inhibited the growth of the Gram-negative bacteria E. coli and Gram-positive bacteria S. aureus at a concentration of 25 and 50 μg/disc. Compounds (2-4) inhibited the phytopathogenic fungus C. cucurbitarum at 50 μg/disc.