Open AccessOne-Pot-Multicomponent Synthesis of 2,6-Diamino-4-arylpyridine-3,5-dicarbonitrile Derivatives Using Nanomagnetic Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>@ZnCl<sub>2</sub>
Author(s) -
Behrooz Maleki,
Hadi Natheghi,
Vahid Sokhanvaran,
Samaneh Sedigh Ashrafi
Publication year - 2018
Publication title -
indonesian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.273
H-Index - 14
eISSN - 2460-1578
pISSN - 1411-9420
DOI - 10.22146/ijc.33062
Subject(s) - chemistry , malononitrile , catalysis , ammonium acetate , reaction conditions , condensation , solvent , condensation reaction , nuclear chemistry , one pot synthesis , organic chemistry , physics , high performance liquid chromatography , thermodynamics
Nanomagnetic Fe3O4@SiO2@ZnCl2 was used as a simple, cost-effective, and reusable heterogeneous catalyst for the synthesis of 2,6-diamino-4-arylpyridine-3,5-dicarbonitriles by a one-pot-three-component condensation reaction of malononitrile, ammonium acetate, and aldehydes under solvent-free conditions at 110 °C. Simple and mild reaction conditions, facile preparation of the catalyst, the use of a cheap catalyst and easy workup and isolation are notable features of this method.