Open AccessA New Thiourea Compound as Potential Ionophore for Metal Ion Sensor
Author(s) -
Fatimatul Akma Awang Ngah,
Emma Izzati Zakariah,
Imran Fakhar,
Nurul Izzaty Hassan,
Lee Yook Heng,
Bohari Mohd. Yamin,
Siti Aishah Hasbullah
Publication year - 2018
Publication title -
indonesian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.273
H-Index - 14
eISSN - 2460-1578
pISSN - 1411-9420
DOI - 10.22146/ijc.27078
Subject(s) - chemistry , thiourea , titration , ionophore , stoichiometry , proton nmr , dissociation constant , binding constant , equilibrium constant , stability constants of complexes , molar conductivity , inorganic chemistry , metal ions in aqueous solution , metal , molar ratio , dissociation (chemistry) , analytical chemistry (journal) , aqueous solution , stereochemistry , binding site , organic chemistry , elemental analysis , calcium , biochemistry , receptor , catalysis
A new thiourea compound, 2,2-oxybis(ethyl)-4-(1-naphthyl)-3-thiourea 3 has been synthesized and characterized by using FTIR, 1H-NMR, 13C-NMR, and MS spectroscopy. The binding properties of with various cations were also carried out using ‘naked eye’, UV-vis and 1H-NMR titration experiments. This compound exhibited effective binding for Hg2+ in the presence of other cations, such as Ag+, Ni2+, Sn2+, Zn2+, Fe2+, Cu2+, and Pb2+. Continuous variation titration experiments were conducted in order to determine the binding behavior for Hg2+. Stoichiometry of the host and guest binding interactions were also determined using continuous variation titration experiments and plotting molar-ratio curves. Pearson Product moment method was employed to calculate the correlation coefficient, and non-linear regression equation was used to calculate dissociation constant Kd. Molar-ratio and binding constant data substantiated the presence of binding sites for the compound 3.