Open AccessIsolation and Antioxidant and Antibacterial Activity of Flavonoid from <i>Ficus variegate</i> Blume
Author(s) -
Rolan Rusli,
Bela Apriliaingsih,
Agung Rahmadani,
Lizma Febrina,
Vina Maulidya,
Jaka Fadraersada
Publication year - 2019
Publication title -
indonesian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.273
H-Index - 14
eISSN - 2460-1578
pISSN - 1411-9420
DOI - 10.22146/ijc.23947
Subject(s) - chemistry , maceration (sewage) , ethyl acetate , column chromatography , flavonoid , methanol , solvent , antibacterial activity , ficus , antioxidant , chromatography , dichloromethane , hexane , traditional medicine , organic chemistry , botany , bacteria , medicine , materials science , biology , composite material , genetics
Ficus variegata Blume is specific plant of east Kalimantan. Flavonoid compound of Ficus variegata Blume was isolated by vacuum liquid and column chromatography, with previously extracted by maceration method using n-hexane and methanol, and fractination using ethyl acetate solvent. Eluent used in isolation were n-hexane:ethyl acetate (8:2). The results of elucidation structure by using spectroscopy methods (GC-MS, NMR, and FTIR) was obtained 5-Hidroxy-2-(4-methoxy-phenyl)-8,8-dymethyl-8H-pyrano[2,3-f] chromen-4-one. This compound has an antibacterial and antioxidant activities.