Open AccessISOLATION AND STRUCTURE DETERMINATION OF BISDEMTHYLAAPTAMINE FROM BUNAKEN MARINE PARK SPONGE <i>Aaptos, sp.</i>
Author(s) -
Wilson Rombang,
Rymond J. Rumampuk,
Ponis Tarigan,
Anthony J. Herlt,
Lewis N. Mander
Publication year - 2010
Publication title -
indonesian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.273
H-Index - 14
eISSN - 2460-1578
pISSN - 1411-9420
DOI - 10.22146/ijc.21881
Subject(s) - chemistry , sponge , alkaloid , electrospray ionization , mass spectrometry , stereochemistry , chromatography , botany , biology
Bisdemethylaaptamine, an alkaloid naphtyridine with molecular weight 200 and formulae molecule C11H8N2O2 has been isolated from Bunaken Marine Park sponge Aaptos sp. Isolation was done by using several stages of column chromatography and high performance liquid chromatography. Molecular weight of this naphtyridine alkaloid was determined by electron ionization (EI) and electrospray ionization (ESI) mass spectroscopies and its structure assigned to be 8,9-dihydroxy-1H-benzo[d,e][1,6]naphtyridine by proton and carbon nuclear magnetic resonances (1H and 13C-NMR). Keywords: Sponge, Aaptos sp., naphtyridine alkaloid, bisdemethylaaptamin