6,6’-DIMETHOXY-4,4’-DIHYDROXY-3’,2’-FURANO-ISOFLAVANE, A NEW COMPOUND FROM Melochia umbellata (Houtt.) Stapf var. Degrabrata K. (Paliasa) | Zendy

Erwin Erwin | Zendy; Alfian Noor | Zendy; Nunuk Hariani Soekamto | Zendy; Tjodi Harlim | Zendy

Open Access

6,6’-DIMETHOXY-4,4’-DIHYDROXY-3’,2’-FURANO-ISOFLAVANE, A NEW COMPOUND FROM Melochia umbellata (Houtt.) Stapf var. Degrabrata K. (Paliasa)

Author(s) -

Erwin Erwin,

Alfian Noor,

Nunuk Hariani Soekamto,

Tjodi Harlim

Publication year - 2010

Publication title -

indonesian journal of chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.273

H-Index - 14

eISSN - 2460-1578

pISSN - 1411-9420

DOI - 10.22146/ijc.21463

Subject(s) - chemistry , chloroform , brine shrimp , carbon 13 nmr , traditional medicine , stereochemistry , proton nmr , organic chemistry , medicine

Using data from UV, IR, 1H-NMR, 13C-NMR, dan NMR-2D analysis, a compound of 6,6'-dimethoxy-4,4'-dihydroxy-3',2'-furano-isoflavane (1) was successfully isolated from chloroform fraction of heartwood in Melochia umbellata (Houtt.) Stapf var. Degrabarata K (Paliasa). Hitherto no report of such compound found in literature. The compound however has not shown a significant bioactivity according to either brine shrimp lethality test or evaluation of anti tumor activity against leukemia murine cell (P-388). Keywords: isoflavane, heartwood, chloroform and Melochia umbellata

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