Open AccessDexmedetomidine Protects Human Renal Tubular Epithelial HK-2 Cells against Hypoxia/Reoxygenation Injury by Inactivating Endoplasmic Reticulum Stress Pathway.
Author(s) -
Mingyu Zhai,
Mingming Han,
Xiang Huang,
Fang Kang,
Cheng Yang,
Juan Li
Publication year - 2021
Publication title -
doaj (doaj: directory of open access journals)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.712
H-Index - 29
eISSN - 2228-5814
pISSN - 2228-5806
DOI - 10.22074/cellj.2021.7220
Subject(s) - apoptosis , chop , viability assay , dexmedetomidine , biology , hypoxia (environmental) , endoplasmic reticulum , western blot , microbiology and biotechnology , flow cytometry , endocrinology , mtt assay , andrology , medicine , pharmacology , biochemistry , chemistry , gene , organic chemistry , sedation , oxygen
The study was aimed to investigate the effects and potential mechanisms of Dexmedetomidine (Dex) on hypoxia/reoxygenation (H/R) injury in human renal tubular epithelial HK-2 cells.