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Personalized Medicine and Its Ethical Challenges
Author(s) -
Wolpe Paul Root
Publication year - 2009
Publication title -
world medical and health policy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.326
H-Index - 11
ISSN - 1948-4682
DOI - 10.2202/1948-4682.1022
Subject(s) - personalized medicine , precision medicine , pharmacogenetics , engineering ethics , subject (documents) , psychology , medicine , computer science , bioinformatics , engineering , biology , biochemistry , pathology , library science , gene , genotype
Personalized medicine is an emerging term for a medical philosophy that uses a person's individual clinical, genetic, genomic, and environmental information to tailor a treatment plan that will maximize efficacy and safety for that individual. While the technology offers much promise, it also is also challenged by some ethical and social questions in both its clinical application and in its research enterprise. Questions about privacy, safety, phenotypical expression, drug interactions, and genetic vs. social group identities will challenge clinical pharmacogenetics. Research studies raise some similar issues, as well as fairness in subject selection. Finally, personalized medicine will change the economics of drug production and distribution. Issues such as these and other complications of the coming focus on personalized medicine are discussed.