Open AccessCollaborative Biomedicine in the Age of Big Data: The Case of Cancer
Author(s) -
Anees Shaikh,
Atul J. Butte,
Sheri D. Schully,
William S. Dalton,
Muin J. Khoury,
Bradford W. Hesse
Publication year - 2014
Publication title -
jmir. journal of medical internet research/journal of medical internet research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.446
H-Index - 142
eISSN - 1439-4456
pISSN - 1438-8871
DOI - 10.2196/jmir.2496
Subject(s) - biomedicine , precision medicine , personalized medicine , informatics , big data , sociotechnical system , health care , cancer prevention , health informatics , data science , medicine , cancer , computer science , knowledge management , engineering , political science , bioinformatics , data mining , pathology , law , electrical engineering , biology
Biomedicine is undergoing a revolution driven by high throughput and connective computing that is transforming medical research and practice. Using oncology as an example, the speed and capacity of genomic sequencing technologies is advancing the utility of individual genetic profiles for anticipating risk and targeting therapeutics. The goal is to enable an era of “P4” medicine that will become increasingly more predictive, personalized, preemptive, and participative over time. This vision hinges on leveraging potentially innovative and disruptive technologies in medicine to accelerate discovery and to reorient clinical practice for patient-centered care. Based on a panel discussion at the Medicine 2.0 conference in Boston with representatives from the National Cancer Institute, Moffitt Cancer Center, and Stanford University School of Medicine, this paper explores how emerging sociotechnical frameworks, informatics platforms, and health-related policy can be used to encourage data liquidity and innovation. This builds on the Institute of Medicine’s vision for a “rapid learning health care system” to enable an open source, population-based approach to cancer prevention and control.