Open AccessHungry bone syndrome in delay diagnosed primary hyperparathyroidism with fi brocystic osteitis: A case report
Author(s) -
Karina Pogosian,
Liubov Yanevskaya,
A. N. Semenova,
M. A. Molotkova,
Г. В. Беркович,
Д. В. Рыжкова,
Lidia Belousova,
U. A. Tsoy
Publication year - 2022
Publication title -
medicinskij vestnik ûga rossii
Language(s) - English
Resource type - Journals
eISSN - 2618-7876
pISSN - 2219-8075
DOI - 10.21886/2219-8075-2022-13-1-102-108
Subject(s) - medicine , osteitis , osteitis fibrosa cystica , nephrocalcinosis , primary hyperparathyroidism , cinacalcet , parathyroid hormone , secondary hyperparathyroidism , surgery , hyperparathyroidism , complication , calcium , osteomyelitis , kidney
Fibrocystic osteitis is a rare but severe primary hyperparathyroidism (PHPT) complication. We describe a 66-year-old female presented with fi brocystic osteitis and nephrocalcinosis with eGFR reduction to CKD stage 4 due to primary hyperparathyroidism. Delayed diagnosis of long-term hypercalcemia, high parathyroid hormone level, unsubstituted 25(OH)D defi ciency, and the use of bisphosphonates in high doses caused development of «hungry bones» syndrome in early postoperative period. Severe hypocalcemia required prescription of active and native vitamin D metabolites, oral calcium supplements as well as intravenous calcium. Delay in diagnosis of PHPT with fi brocystic osteitis formation led to lower well-being, reduced quality of life and also provoked sever postoperative hypocalcemia («hungry bone» syndrome).