Open AccessThe use of atypical antipsychotics in the therapy of depressive episodes in patients with bipolar disorder
Author(s) -
E. A. Streltsov
Publication year - 2021
Publication title -
medicinskij vestnik ûga rossii
Language(s) - English
Resource type - Journals
eISSN - 2618-7876
pISSN - 2219-8075
DOI - 10.21886/2219-8075-2021-12-3-32-35
Subject(s) - bipolar disorder , clinical global impression , psychology , rating scale , psychiatry , medline , depression (economics) , randomized controlled trial , meta analysis , clinical psychology , medicine , alternative medicine , mood , developmental psychology , pathology , political science , law , economics , macroeconomics , placebo
This literature review addresses the effi cacy and safety of atypical antipsychotics in patients with bipolar depression. Th e results of randomized studies and systematic meta-analyses of recent years were revised in detail. The effi cacy of the drug intake was reviewed for the following key research points: Clinical General Impression of Condition Severity Scale (CGI-S) and Montgomery-Asberg Depression Rating Scale (MADRS). A systematic literature search was carried out using Scopus, Web of Science, MedLine, elibrary, and other databases.